American depository receipts of European stocks were trading 1.68% lower to 116.93 on the Bank of New York Mellon Europe ADR Index on Thursday.

In continental Europe, the gainers were led by software company Talend (TLND) and Flamel Technologies (FLML), a specialty pharmaceutical company, which rose 3.6% and 1.8% respectively. They were followed by semiconductor company STMicroelectronics (STM), and medical equipment firm Edap (EDAP), which were up 1.3% and 0.7% each.

The decliners in continental Europe were led by Aegon (AEG), a life insurance, pensions and asset management company, and genome engineering company Cellectis (CLLS), which lost 4.5% and 4.4% each. They were followed by steel and mining company ArcelorMittal (MT), and Spanish bank Banco Santander (SAN), which dropped 3.3% and 3.2% respectively.

In the U.K. and Ireland, the gainers were led by gold mining company Randgold Resources (GOLD), and biopharmaceutical company Shire (SHPG), which rose 1.4% and 0.30% respectively. They were followed by tobacco company British American Tobacco (BTI), and electricity and gas utility National Grid (NGG), which edged 0.2% higher each.

The decliners in the U.K. and Ireland were led by mining company BHP Billiton (BBL), and insurance provider Prudential (PUK), which shed 5.1% and 4.8% respectively. They were followed by mining and natural resources company Rio Tinto (RIO) and biopharmaceutical firm Akari Therapeutics (AKTX), which fell 4.5% and 4.4% each.

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